No introduction is required for Alexander the Great, the ancient Greek King of Macedon (336–323 BC). He was one of the most successful military commanders of all time and is presumed undefeated in battle. By the time of his death, he had conquered the Achaemenid Persian Empire, adding it to Macedon's European territories; according to some modern writers, this was most of the world as known to the ancient Greeks. His conquests included Anatolia, the Levant, Egypt, Bactria and Mesopotamia, and he extended the boundaries of his own empire as far as Punjab, India.
If not for tuberculosis, we would not have lost the Mathematical genius , Ramanujam at young age.